Pharmaceutical Litigation
Zyprexa®
Manufacturer:
Eli Lilly
Uses: Schizophrenia, Psychosis, Bipolar Mania
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| Zyprexa |
Zyprexa (sometimes called olanzapine) is a popular antipsychotic drug
administered for treatment of schizophrenia and bipolar disorder. Manufactured
by Eli Lilly, Zyprexa has been prescribed to more than 12 million people
worldwide since its introduction.
The side effects linked to Zyprexa involve drastic changes in patients blood
sugar levels. In studies in Europe and Japan, researchers have discovered dozens
of cases in which patients suffered injuries from changes in their blood glucose
and several patients reportedly died of complications from Zyprexa-induced blood
sugar elevation. Patients with diabetes or high blood sugar are at the greatest
risk as Zyprexa seems to aggravate their disease. However, Zyprexa may also
cause serious side effects in otherwise healthy patients being treated for
mental disorders.
A study at Duke University in July of 2002 further showed a connection
between Zyprexa and diabetes. The study documented nearly 300 cases of diabetes
in people using Zyprexa. with many of the cases developing within 6 months of
Zyprexa use. The company resisted efforts to advise Zyprexa users to monitor
blood glucose levels and only recently added labeling language about a possible
link between Zyprexa and diabetes following the request by the Food and Drug
Administration last September.
The FDA recommends that patients using Zyprexa and antipsychotic drugs be
monitored for blood-sugar abnormalities, especially when they have risk factors
including obesity and a family history of diabetes.
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Side Effects
- Diabetes Mellitus
- Pancreatitis
- Hyperglycemia
- Diabetic Ketoacidosis
- Diabetic Coma
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